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People’s lives are wrecked by debilitating pain and fatiguing illnesses. The guardians of medical knowledge perpetuate their suffering by targeting symptoms, not causes, and by ignoring medical evidence that chronic infections cause pain and fatigue. Professor Garth Nicolson of the Institute for Molecular Medicine in Huntingdon Beach, California, outlines the tragedy of the ‘black hole’ in medical training which has led to unimaginable suffering and the neglect of society’s most wretched and marginalized members: those suffering from unrelenting pain and fatigue.